Yolk sac macrophages are the first to seed the developing heart; however, owing to a lack of accessible tissue, there is no understanding of their roles in human heart development and function. In ...

Our research challenges the assumption that heart structure is uniform across mammals. Instead, subtle but crucial differences in heart anatomy and function have emerged in response to unique ...

Researchers mapped 442,239 single nuclei from nonfailing human hearts to chart how cardiac cells change from fetal ...

The heart requires substantial energy to sustain its contractile function. Cardiomyocytes reach full functional maturity through postnatal development. During this process, key aspects such as fuel ...

A team of biomechanical engineers at the University of New South Wales, working with a colleague from Queensland University of Technology and cardiac surgeons at St Vincent's Hospital, Sydney, has ...

Researchers at RCSI University of Medicine and Health Sciences have developed an artificial model of the mitral heart valve ...

The heart has long been thought to be controlled solely by the autonomic nervous system, which transmits signals from the brain. The heart's neural network, which is embedded in the superficial layers ...

An international research team from Swansea University and UBC Okanagan (UBCO) has uncovered a new insight into human evolution by comparing humans' hearts with those of other great apes. Despite ...

A new gene therapy can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the amount of blood the heart can pump and dramatically improves ...

Researchers at the Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, and the University of Utah School of Medicine, have demonstrated that a gene therapy can ...

In a groundbreaking development, Irish-based researchers have developed a model of a vital heart valve that mimics the ...