A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's ...

Life’s instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing RNA in eukaryotic cells and eventually giving rise to proteins. Scientists ...

When the molecular machinery in our cells gets to work transcribing the genetic information encoded in DNA into messenger RNA (mRNA), it pauses shortly after starting. Known as promoter-proximal ...

Every living cell must interpret its genetic code - a sequence of chemical letters that governs countless cellular functions. A new study by researchers from the Center for Theoretical Biological ...

A principle of DNA synthesis that has dominated biology textbooks for decades could be upended. An enzyme has been discovered ...

The study, authored by Tripti Midha, Anatoly Kolomeisky and Oleg Igoshin and published in the Proceedings of the National Academy of Sciences. Every living cell must interpret its genetic code — a ...

Thanks to a first-of-its-kind platform, we are starting to understand how the molecular engine responsible for transcription in mammals controls its speed. A team of researchers from The Rockefeller ...

A new technique shows DNA binding domains are not central to transcription factor targeting in human cells, unlike in ...

Remarkably, 98 percent of our DNA does not code for genes. Once considered “junk DNA,” it is now well appreciated that these ...